Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EPOR | P19235 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266036 | 0.82 | ABCB1 (0.43) | ABCB1SMN1; SMN2F2PLAUPLAT | |
| SCHEMBL7328213 | 0.81 | ABCB1 (0.47) | ABCB1EPORLTA4HALDH1A1TRPM8 | |
| SCHEMBL11639032 | 0.79 | CTRB1 (0.39) | ABCB1KMT2AALDH1A1MAPTCTRB1 | |
| SCHEMBL7333726 | 0.75 | ABCB1 (0.43) | ABCB1MEN1KMT2AALDH1A1MAPT | |
| Water SCHEMBL11367764 | 0.75 | ITGB3 (0.35) | CTRB1 | |
| SCHEMBL10443979 | 0.74 | SLC15A1 (0.40) | ABCB1PKMLTA4HMEN1KMT2A | |
| SCHEMBL9320151 | 0.74 | TPSAB1 (0.43) | MAPT | |
| SCHEMBL7267095 | 0.74 | POLB (0.45) | MAPT | |
| SCHEMBL9748132 | 0.74 | L3MBTL1 (0.43) | ALDH1A1MAPT | |
| SCHEMBL7938097 | 0.73 | ANPEP (0.38) | MEN1KMT2AALDH1A1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337339-A | Process for preparation of folic acid derivatives | BAKER INSTRUMENTS CORP. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4326060-A | 6-FORMYLPTERIN, P-AMINOBENZOYL AMINO ACID | BAKER INSTRUMENTS CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
| US-4314988-A | Folic acid derivatives and process for preparation | BAKER INSTRUMENTS CORP. (US) | 1982-02-09 | — | — | US | disclosed |
| US-4298735-A | Folic acid derivatives | UNION CARBIDE CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |