Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.57 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3011111 | 0.88 | RAB9A (0.67) | GAARAB9ALNPEPALDH1A1LMNA | |
| SCHEMBL3011109 | 0.88 | RAB9A (0.67) | GAARAB9ALNPEPALDH1A1LMNA | |
| SCHEMBL13885677 | 0.88 | GAA (0.73) | GAARAB9ALNPEPERAP2ERAP1 | |
| SCHEMBL4364268 | 0.85 | TSHR (0.58) | GAARAB9ALNPEPERAP2ERAP1 | |
| SCHEMBL4362313 | 0.85 | TSHR (0.58) | GAARAB9ALNPEPERAP2ERAP1 | |
| SCHEMBL3928164 | 0.85 | LNPEP (0.67) | GAARAB9ALNPEPERAP2ERAP1 | |
| SCHEMBL3928165 | 0.85 | LNPEP (0.67) | GAARAB9ALNPEPERAP2ERAP1 | |
| SCHEMBL6030105 | 0.84 | GAA (0.68) | GAARAB9ALNPEPERAP2ERAP1 | |
| SCHEMBL2402461 | 0.84 | ALDH1A1 (0.67) | TSHRALDH1A1TACR1MDM4MDM2 | |
| SCHEMBL7294741 | 0.84 | ALDH1A1 (0.67) | TSHRALDH1A1TACR1MDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337339-A | Process for preparation of folic acid derivatives | BAKER INSTRUMENTS CORP. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4326060-A | 6-FORMYLPTERIN, P-AMINOBENZOYL AMINO ACID | BAKER INSTRUMENTS CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
| US-4314988-A | Folic acid derivatives and process for preparation | BAKER INSTRUMENTS CORP. (US) | 1982-02-09 | — | — | US | disclosed |
| US-4298735-A | Folic acid derivatives | UNION CARBIDE CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |