Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273822 | 0.89 | DRD2 (0.53) | ABCB1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11280762 | 0.88 | DRD3 (0.56) | DRD2HTR1AHTR2ADRD3HRH1 | |
| SCHEMBL11273882 | 0.88 | DRD2 (0.55) | ABCB1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11271731 | 0.88 | SLC6A4 (0.52) | ABCB1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11263300 | 0.86 | DRD2 (0.53) | ABCB1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11274363 | 0.86 | DRD2 (0.59) | ABCB1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11282244 | 0.85 | DRD2 (0.53) | KDM4EDRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11277199 | 0.85 | SLC6A2 (0.56) | ABCB1KDM4EDRD2HTR1AHTR2A | |
| SCHEMBL11273991 | 0.82 | DRD2 (0.48) | ABCB1KDM4EDRD2HTR1AHTR2A | |
| SCHEMBL11269168 | 0.81 | ADRA1D (0.68) | DRD2HTR1AHTR2ADRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |
| EP-0021368-A1 | Piperazinylalkoxyindanes and acid addition salts thereof | MITSUBISHI KASEI CORPORATION (JP) | 1981-01-07 | — | — | EP | disclosed |