Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266112 | 0.88 | ABCB1 (0.55) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11266553 | 0.88 | HTR1A (0.62) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11283459 | 0.88 | KCNH2 (0.60) | SIGMAR1 | |
| SCHEMBL11292019 | 0.86 | TSHR (0.59) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11270622 | 0.86 | DRD3 (0.57) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11270104 | 0.86 | HTR1A (0.56) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11271731 | 0.85 | SLC6A4 (0.52) | DRD3HTR1ADRD2HTR2ASIGMAR1 | |
| SCHEMBL11282244 | 0.85 | DRD2 (0.53) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11273685 | 0.85 | HTR2A (0.53) | DRD3HTR1ADRD2HTR2AHTR4 | |
| Hydrochloric Acid SCHEMBL11284442 | 0.85 | HTR1A (0.56) | DRD3HTR1AHRH1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |
| EP-0021368-A1 | Piperazinylalkoxyindanes and acid addition salts thereof | MITSUBISHI KASEI CORPORATION (JP) | 1981-01-07 | — | — | EP | disclosed |