Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260580 | 0.88 | DGKA (0.41) | DGKADNM1NLRP3GBA1LMNA | |
| SCHEMBL11259971 | 0.80 | DGKA (0.41) | DGKADNM1NLRP3LMNAHTR2C | |
| SCHEMBL11259969 | 0.80 | DGKA (0.41) | DGKADNM1NLRP3LMNAHTR2C | |
| SCHEMBL11269957 | 0.78 | DGKA (0.43) | DGKADNM1NLRP3LMNAPAM | |
| SCHEMBL11269955 | 0.78 | DGKA (0.43) | DGKADNM1NLRP3LMNAPAM | |
| SCHEMBL11266279 | 0.76 | LMNA (0.42) | LMNAALDH1A1KMT2ASMN1; SMN2PRKCA | |
| SCHEMBL11251328 | 0.74 | DGKA (0.47) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL11262663 | 0.74 | DGKA (0.47) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9695229 | 0.73 | DGKA (0.53) | DGKADNM1LMNAPAMHTR2C | |
| SCHEMBL9550459 | 0.73 | DGKA (0.53) | DGKADNM1LMNAPAMHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346087-A | CORROSION RESISTANCE | TOHO CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |