Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.71 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.69 |
| ▸ | MAOB | P27338 | 5/20 | 0.69 |
| ▸ | CA12 | O43570 | 4/20 | 0.69 |
| ▸ | CA1 | P00915 | 4/20 | 0.69 |
| ▸ | CA6 | P23280 | 4/20 | 0.69 |
| ▸ | CA7 | P43166 | 4/20 | 0.69 |
| ▸ | CA9 | Q16790 | 4/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | CA4 | P22748 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | CA5A | P35218 | 3/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.69 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.69 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.69 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229324 | 0.92 | MAOB (0.60) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL27080004 | 0.89 | MAOB (0.68) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL29362684 | 0.86 | MAOA (0.54) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL29575367 | 0.85 | CA12 (0.65) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL29785071 | 0.83 | MAOA (1.00) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL979779 | 0.83 | MAOA (1.00) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL9068782 | 0.81 | KDM4E (1.00) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL31315658 | 0.81 | MAOA (0.69) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL9068774 | 0.81 | MAOA (0.69) | MAOAGPR35MAOBCA12CA1 | |
| SCHEMBL569881 | 0.81 | GPR35 (1.00) | MAOAGPR35MAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343938-A | 7-[Dα-(Coumarin-3-carboxamido)arylacetamido]-cephalosporanic acids or salts | AMERICAN CYANAMID COMPANY (US) | 1982-08-10 | — | — | US | disclosed |
| US-4317774-A | 6-[D-α-(Coumarin-3-carboxamido)arylacetamido]-penicillanic acids or salts | AMERICAN CYANAMID COMPANY (US) | 1982-03-02 | — | — | US | disclosed |