Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281833 | 0.85 | — | — | |
| SCHEMBL11281672 | 0.79 | PRSS1 (0.36) | — | |
| SCHEMBL11280191 | 0.77 | SCN4A (0.35) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11413787 | 0.76 | HTR3E (0.30) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11408944 | 0.76 | HTR3E (0.37) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11274873 | 0.75 | — | — | |
| SCHEMBL11405499 | 0.73 | TP53 (0.33) | — | |
| SCHEMBL11272594 | 0.72 | SIGMAR1 (0.49) | — | |
| SCHEMBL11406819 | 0.72 | HTR3E (0.34) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11404736 | 0.72 | RAPGEF4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326075-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4203920-A | ANTIDIARRHEAL | WILLIAM H. RORER, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |