SCHEMBL11266568

SCHEMBL11266568

COC(=O)C(c1ccc(NC(C)=O)c(Cl)c1)C1CC1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 12/20 0.64
SLC6A2 P23975 5/20 0.59
SLC6A4 P31645 5/20 0.59
ALDH1A1 P00352 1/20 0.47
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11275292 0.79 SLC6A3 (0.67) SLC6A3SLC6A2SLC6A4
SCHEMBL10006175 0.79 SLC6A3 (1.00) SLC6A3SLC6A2SLC6A4
SCHEMBL11277396 0.78 DHODH (0.55) SLC6A3SLC6A2SLC6A4ALDH1A1CA1
SCHEMBL9644018 0.76 SLC6A3 (0.62) SLC6A3SLC6A2SLC6A4
SCHEMBL10620579 0.74 CA1 (0.54) ALDH1A1CA1CA2CA9
SCHEMBL11274171 0.73 SLC6A3 (0.62) SLC6A3SLC6A2SLC6A4
SCHEMBL3554782 0.71 SLC6A3 (0.72) SLC6A3SLC6A2SLC6A4
SCHEMBL9400181 0.70 RAB9A (0.63) ALDH1A1CA1CA2CA9
SCHEMBL17145458 0.70 SLC6A3 (0.55) SLC6A3SLC6A2SLC6A4
SCHEMBL28628509 0.70 SLC6A3 (0.60) SLC6A3SLC6A2SLC6A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4337264-A ANALGESICS, ANTIINFLAMMATORY AGENTS AND FUNGICIDES CIBA-GEIGY CORPORATION (US) 1982-06-29 US disclosed
US-4316850-A ANTINFLAMMATORY AGENTS CIBA-GEIGY CORPORATION (US) 1982-02-23 US disclosed
US-4264619-A Tertiary aminoacids CIBA-GEIGY CORPORATION (US) 1981-04-28 US disclosed
US-4163788-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1979-08-07 US disclosed
US-4126691-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1978-11-21 US disclosed
US-3997669-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1976-12-14 US disclosed