Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701464 | 0.94 | SLC6A3 (0.63) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11274171 | 0.83 | SLC6A3 (0.62) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9644018 | 0.83 | SLC6A3 (0.62) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28628509 | 0.83 | SLC6A3 (0.60) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL24662249 | 0.81 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL30375011 | 0.81 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11277396 | 0.80 | DHODH (0.55) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11163723 | 0.79 | POLB (0.41) | — | |
| SCHEMBL9154015 | 0.79 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4247382 | 0.79 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150568-B2 | Compositions and methods for modulating FXR | NOVARTIS AG (CH) | 2015-10-06 | — | — | US | disclosed |
| US-9150568-B2 | Compositions and methods for modulating FXR | NOVARTIS AG (CH) | 2015-10-06 | — | — | US | disclosed |