Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27726737 | 0.77 | LMNA (0.47) | BCAT2GAALMNACTSDEPHX1 | |
| SCHEMBL28027566 | 0.75 | LMNA (0.46) | BCAT2GAALMNACTSDEPHX1 | |
| SCHEMBL9750459 | 0.75 | BCAT2 (0.44) | BCAT2GAALMNACTSDALDH1A1 | |
| SCHEMBL27540557 | 0.74 | LMNA (0.45) | BCAT2GAALMNAKMT2ACTSD | |
| SCHEMBL10338251 | 0.70 | GAA (0.50) | BCAT2GAALMNAMEN1KMT2A | |
| SCHEMBL27445869 | 0.70 | MPO (0.38) | LMNAACP3ALDH1A1MPOCYP2D6 | |
| SCHEMBL575475 | 0.69 | MPO (0.40) | ACP3ALDH1A1MPO | |
| SCHEMBL2489197 | 0.69 | MPO (0.40) | ACP3ALDH1A1MPOCYP2D6SRC | |
| SCHEMBL28134112 | 0.69 | BCAT2 (0.42) | BCAT2GAALMNAMEN1KMT2A | |
| SCHEMBL27480645 | 0.69 | MEN1 (0.44) | BCAT2LMNAMEN1KMT2ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315020-A | Oxazoline (trifluoroethyl) amine | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| US-4315019-A | Novel aryltrifluoroethylamines and processes for producing the same | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| US-4267345-A | 2-//PYRROL-2-YL, THIEN-2-YL, OR FUR-2-YL/-ALPHA-TRIFLUOROALKYL-AMINOOXAZOLINES; HYPOTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1981-05-12 | — | — | US | disclosed |