Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27259664 | 0.74 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPK1POLBMEN1 | |
| SCHEMBL16417100 | 0.67 | NOTUM (0.50) | LMNACYP3A4TSHRCA12CA1 | |
| SCHEMBL1126625 | 0.67 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1POLBMEN1 | |
| SCHEMBL4649372 | 0.67 | CA12 (0.41) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL15061872 | 0.65 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNACYP1A2CYP3A4 | |
| SCHEMBL27259271 | 0.65 | APLNR (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL1988083 | 0.65 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPK1POLBMEN1 | |
| SCHEMBL23498573 | 0.65 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL23498902 | 0.65 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL6825057 | 0.64 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MAPK1POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |