Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264945 | 0.90 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNATBXAS1LTA4H | |
| SCHEMBL11259944 | 0.90 | KDM4E (0.48) | ALDH1A1KDM4ELMNA | |
| SCHEMBL11261214 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNATBXAS1LTA4H | |
| SCHEMBL11265246 | 0.90 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNATBXAS1LTA4H | |
| SCHEMBL11269393 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNATBXAS1LTA4H | |
| SCHEMBL11267811 | 0.89 | CYP19A1 (0.44) | ALDH1A1LMNATBXAS1KMT2ASMN1; SMN2 | |
| SCHEMBL11260695 | 0.88 | KDM4E (0.46) | ALDH1A1KDM4ELMNATBXAS1 | |
| SCHEMBL11265945 | 0.88 | HMOX1 (0.38) | QPCTCYP19A1 | |
| SCHEMBL11259567 | 0.86 | HMOX1 (0.41) | — | |
| SCHEMBL11257105 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNATBXAS1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |