Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260381 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNATBXAS1LTA4H | |
| SCHEMBL11266883 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNATBXAS1LTA4H | |
| SCHEMBL11261656 | 0.90 | MEN1 (0.46) | ALDH1A1KDM4ELMNATBXAS1LTA4H | |
| SCHEMBL11260418 | 0.88 | QPCT (0.39) | ALDH1A1KDM4ETBXAS1QPCTHMOX1 | |
| SCHEMBL11252522 | 0.86 | CYP19A1 (0.38) | HMOX1 | |
| SCHEMBL11267712 | 0.86 | CYP19A1 (0.46) | ALDH1A1KMT2AQPCTHMOX1 | |
| SCHEMBL11263808 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNATBXAS1LTA4H | |
| SCHEMBL11264326 | 0.85 | HMOX1 (0.46) | ALDH1A1KDM4EMAPK1HMOX1 | |
| SCHEMBL11255906 | 0.85 | CYP2A6 (0.46) | KDM4EHMOX1 | |
| SCHEMBL11260873 | 0.85 | CYP19A1 (0.43) | TBXAS1LTA4HKMT2AQPCTHMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |