Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257672 | 0.88 | MAPT (0.54) | MAPTPOLBMAPK1TDP1NPSR1 | |
| SCHEMBL11264549 | 0.85 | PTGS2 (0.59) | MAPTPOLBMAPK1TDP1NPSR1 | |
| SCHEMBL11421535 | 0.83 | MAPT (0.65) | MAPTPOLBMAPK1TDP1NPSR1 | |
| SCHEMBL11421528 | 0.81 | MAPT (0.52) | MAPTPOLBMAPK1TDP1NPSR1 | |
| SCHEMBL656776 | 0.81 | PTGS2 (0.66) | MAPTPOLBNPSR1GAAHTT | |
| SCHEMBL11266959 | 0.80 | MAPT (0.65) | MAPTPOLBMAPK1TDP1NPSR1 | |
| SCHEMBL11264402 | 0.80 | MAPK1 (0.85) | MAPTPOLBMAPK1TDP1NPSR1 | |
| SCHEMBL5174292 | 0.77 | MAPT (0.78) | MAPTPOLBMAPK1TDP1NPSR1 | |
| SCHEMBL9188865 | 0.77 | PTGS2 (0.61) | MAPTNPSR1GAAHTTKDM4E | |
| SCHEMBL5066833 | 0.77 | HPGD (0.54) | MAPTPOLBMAPK1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323691-A | Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters | ABBOTT LABORATORIES (US) | 1982-04-06 | — | — | US | disclosed |