Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKBIA | P25963 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269034 | 0.84 | SLC40A1 (0.49) | NFKBIARELASLC40A1MEN1KMT2A | |
| SCHEMBL10711350 | 0.80 | LMNA (0.62) | NFKBIARELASLC40A1MEN1KMT2A | |
| SCHEMBL3837982 | 0.80 | NFKBIA (0.60) | NFKBIARELASLC40A1MEN1KMT2A | |
| SCHEMBL10888517 | 0.79 | NFKBIA (0.58) | NFKBIARELASLC40A1MEN1KMT2A | |
| SCHEMBL11267052 | 0.78 | LMNA (0.67) | MEN1KMT2ATDP1LMNAAURKA | |
| SCHEMBL11272841 | 0.77 | NFKBIA (0.48) | NFKBIARELASLC40A1MEN1KMT2A | |
| SCHEMBL6557188 | 0.76 | SLC40A1 (0.48) | NFKBIARELASLC40A1MEN1KMT2A | |
| SCHEMBL3644476 | 0.72 | TSHR (0.62) | NFKBIARELASLC40A1MEN1KMT2A | |
| SCHEMBL2986277 | 0.71 | NPSR1 (0.65) | NFKBIARELASLC40A1MEN1KMT2A | |
| SCHEMBL8864437 | 0.71 | NFKBIA (0.51) | NFKBIARELASLC40A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333936-A | Novel amidino-benzylpyrimidines, processes for their manufacture and antibacterial and antiprotozoal use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| EP-0000336-A1 | N-benzylpyrimidinyl-amidines, process for their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1979-01-24 | — | — | EP | disclosed |