Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | DHFR | P00374 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | EDNRA | P25101 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfaperin SCHEMBL151755 | 0.84 | LMNA (0.70) | LMNAAURKADHFRTSHRL3MBTL1 | |
| Sulfaperin SCHEMBL9418724 | 0.83 | LMNA (0.68) | LMNAAURKADHFRTSHRL3MBTL1 | |
| Sulfaperin SCHEMBL16416441 | 0.83 | LMNA (0.68) | LMNAAURKADHFRTSHRL3MBTL1 | |
| SCHEMBL6046849 | 0.81 | LMNA (0.68) | LMNAAURKADHFRTSHRL3MBTL1 | |
| Sulfameter SCHEMBL79417 | 0.80 | LMNA (1.00) | LMNAAURKADHFRTSHRL3MBTL1 | |
| Sulfaperin SCHEMBL7944543 | 0.80 | LMNA (0.65) | LMNAAURKADHFRTSHRL3MBTL1 | |
| Sulfameter SCHEMBL17593237 | 0.79 | LMNA (0.97) | LMNAAURKADHFRTSHRL3MBTL1 | |
| Sulfameter SCHEMBL11137116 | 0.79 | LMNA (0.97) | LMNAAURKADHFRTSHRL3MBTL1 | |
| Sulfameter SCHEMBL27709233 | 0.79 | LMNA (0.97) | LMNAAURKADHFRTSHRL3MBTL1 | |
| Sulfadiazine SCHEMBL24176 | 0.78 | LMNA (1.00) | LMNAAURKADHFRTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333936-A | Novel amidino-benzylpyrimidines, processes for their manufacture and antibacterial and antiprotozoal use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| EP-0000336-A1 | N-benzylpyrimidinyl-amidines, process for their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1979-01-24 | — | — | EP | disclosed |