Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267037 | 1.00 | LSS (0.44) | LSSPPARDKDM4EALDH1A1APP | |
| SCHEMBL10529954 | 0.83 | LTA4H (0.43) | AOC3 | |
| SCHEMBL10529963 | 0.83 | LTA4H (0.43) | AOC3 | |
| SCHEMBL7723533 | 0.82 | LSS (0.39) | LSSPPARDKDM4EALDH1A1APP | |
| SCHEMBL7723537 | 0.82 | LSS (0.39) | LSSPPARDKDM4EALDH1A1APP | |
| SCHEMBL11802298 | 0.82 | LSS (0.47) | LSSPPARDKDM4EALDH1A1APP | |
| SCHEMBL11802292 | 0.82 | LSS (0.47) | LSSPPARDKDM4EALDH1A1APP | |
| SCHEMBL15274492 | 0.81 | L3MBTL1 (0.46) | DRD2DRD4DRD3AOC3MAPT | |
| SCHEMBL1069709 | 0.81 | LMNA (0.48) | KDM4EALDH1A1APPMAPT | |
| SCHEMBL1069708 | 0.81 | LMNA (0.48) | KDM4EALDH1A1APPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019377-B1 | 1-HYDROCARBYLOXYPHENYL-1,2-DIPHENYLALKENE DERIVATIVES, THEIR MANUFACTURE AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-08-04 | — | — | EP | disclosed |
| US-4307111-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-12-22 | — | — | US | disclosed |
| EP-0019377-A1 | 1-Hydrocarbyloxyphenyl-1,2-diphenylalkene derivatives, their manufacture and a pharmaceutical composition containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-11-26 | — | — | EP | disclosed |