Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268181 | 0.89 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C19KDM4EPOLB | |
| SCHEMBL11283747 | 0.84 | KDM4E (0.51) | CYP1A2CYP3A4CYP2C19KDM4ELMNA | |
| SCHEMBL11269004 | 0.83 | EGFR (0.43) | CYP1A2CYP3A4CYP2C19KDM4EPOLB | |
| SCHEMBL11277795 | 0.81 | ALDH1A1 (0.46) | CYP1A2CYP3A4CYP2C19KDM4EPOLB | |
| SCHEMBL11270977 | 0.76 | MAPT (0.40) | CYP1A2CYP3A4CYP2C19KDM4EPOLB | |
| SCHEMBL11273839 | 0.76 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19KDM4EPOLB | |
| SCHEMBL11420117 | 0.76 | MEN1 (0.55) | CYP1A2CYP2C19KDM4EPOLBMAPK1 | |
| SCHEMBL11419618 | 0.75 | ALDH1A1 (0.51) | KDM4EPOLBLMNAMAPK1ALDH1A1 | |
| SCHEMBL11278189 | 0.71 | KDM4E (0.50) | CYP1A2CYP3A4CYP2C19KDM4ELMNA | |
| SCHEMBL11374794 | 0.71 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C19KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |