Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284580 | 0.87 | CSNK2A2 (0.39) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11268181 | 0.77 | CYP1A2 (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11274629 | 0.77 | CYP1A2 (0.40) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11285888 | 0.76 | POLB (0.40) | MAPTPOLBLMNATHRBCSNK2A2 | |
| SCHEMBL11267104 | 0.76 | CYP1A2 (0.47) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11273550 | 0.76 | MAPT (0.39) | MAPTPOLBTHRB | |
| SCHEMBL11074319 | 0.75 | CSNK2A2 (0.59) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11283747 | 0.73 | KDM4E (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11269598 | 0.73 | PKM (0.41) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL12892202 | 0.71 | TP53 (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |