Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253406 | 0.78 | HPGD (0.41) | HPGDLMNAALDH1A1USP2TSHR | |
| SCHEMBL11383418 | 0.77 | TDP1 (0.43) | HPGDLMNAALDH1A1TSHRHTT | |
| SCHEMBL2042737 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TSHRCYP3A4TDP1 | |
| Methane SCHEMBL6122998 | 0.76 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP3A4TDP1 | |
| Water SCHEMBL1685815 | 0.76 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL3110066 | 0.76 | TDP1 (0.34) | ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL29826970 | 0.75 | TDP1 (0.45) | LMNAALDH1A1TSHRMEN1CYP3A4 | |
| SCHEMBL6480647 | 0.75 | TDP1 (0.45) | LMNAALDH1A1TSHRMEN1CYP3A4 | |
| Formic Acid SCHEMBL28477366 | 0.74 | ALDH1A1 (0.32) | ALDH1A1TDP1POLB | |
| SCHEMBL8401122 | 0.73 | TDP1 (0.36) | ALDH1A1TSHRMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358450-A | FOR DECREASING BLOOD CHOLESTEROL | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |
| US-4328227-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | disclosed |