Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214189 | 0.83 | MEN1 (0.40) | LMNAMAPTABCB11MAPK1SMN1; SMN2 | |
| SCHEMBL11264433 | 0.80 | LMNA (0.68) | LMNAMAPTABCB11MAPK1SMN1; SMN2 | |
| SCHEMBL11259163 | 0.78 | MAPT (0.57) | LMNAMAPTABCB11MAPK1MEN1 | |
| SCHEMBL11268767 | 0.78 | MAPT (0.56) | LMNAMAPTABCB11MAPK1MEN1 | |
| SCHEMBL4731655 | 0.75 | LMNA (0.72) | LMNAMAPTABCB11MAPK1SMN1; SMN2 | |
| SCHEMBL11268901 | 0.75 | LMNA (0.72) | LMNAMAPTABCB11MAPK1SMN1; SMN2 | |
| SCHEMBL11267381 | 0.74 | MAPT (0.55) | LMNAMAPTABCB11MAPK1SMN1; SMN2 | |
| SCHEMBL11202443 | 0.74 | L3MBTL1 (0.47) | LMNAMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL11276195 | 0.74 | LMNA (0.57) | LMNAMAPTABCB11MAPK1SMN1; SMN2 | |
| SCHEMBL10604296 | 0.73 | CYP4F2 (0.49) | LMNAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |