Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271902 | 0.92 | ALDH1A1 (0.40) | MAPTRAB9APPARGPPARDPPARA | |
| SCHEMBL11270305 | 0.88 | MAPT (0.39) | MAPTRAB9APPARGPPARDPPARA | |
| SCHEMBL11264984 | 0.86 | KMT2A (0.39) | MAPTRAB9APPARGPPARDPPARA | |
| SCHEMBL11270609 | 0.86 | HCAR1 (0.36) | MAPTPPARGPPARDPPARAPTGS2 | |
| SCHEMBL11270269 | 0.86 | SMN1; SMN2 (0.39) | MAPTRAB9APPARGPPARDPPARA | |
| SCHEMBL11267538 | 0.86 | CYP11B2 (0.32) | CYP11B2 | |
| SCHEMBL11268398 | 0.86 | ALDH1A1 (0.41) | MAPTRAB9APPARGPPARDPPARA | |
| SCHEMBL11278669 | 0.85 | ALDH1A1 (0.42) | MAPTRAB9APPARGPPARDPPARA | |
| SCHEMBL11278370 | 0.85 | PPARD (0.41) | PPARGPPARDPPARACYP11B2 | |
| SCHEMBL11263206 | 0.84 | HCAR1 (0.42) | MAPTRAB9AALDH1A1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350701-A | 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | claimed |
| US-4350701-A | 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |