Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990335 | 0.81 | AR (0.57) | ARTSHRTP53RAB9ASMN1; SMN2 | |
| SCHEMBL1126972 | 0.80 | AR (0.56) | ARHPGDTSHRTP53MAPT | |
| SCHEMBL1127045 | 0.80 | TSHR (0.68) | ARHPGDTSHRMAPTRAB9A | |
| SCHEMBL28645817 | 0.76 | TSHR (0.54) | ARHPGDTSHRMAPTRAB9A | |
| SCHEMBL1126643 | 0.74 | TSHR (0.54) | ARHPGDTSHRTP53MAPT | |
| SCHEMBL1991365 | 0.73 | TSHR (0.50) | HPGDTSHRTP53MAPTRAB9A | |
| SCHEMBL1126728 | 0.71 | AR (0.44) | ARTSHRTP53MAPTALDH1A1 | |
| SCHEMBL21484965 | 0.71 | TSHR (0.55) | HPGDTSHRMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9952023 | 0.70 | TDP1 (0.75) | TSHRSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL1990320 | 0.69 | TSHR (0.48) | ARHPGDTSHRTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |