SCHEMBL11267463

SCHEMBL11267463

CC(N)CC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
MGLL Q99685 2/20 0.32
LMNA P02545 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA13 Q8N1Q1 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18291163 0.86 KMT2A (0.35) KMT2AATMMGLL
SCHEMBL1245548 0.85 MMP1 (0.36) KMT2AATMMGLLLMNACA2
SCHEMBL15643139 0.85 KMT2A (0.36) KMT2AATMMGLL
SCHEMBL17155176 0.84 MAPK1 (0.35) KMT2AATMMGLL
SCHEMBL16310469 0.82 KMT2A (0.37) KMT2AATMMGLL
SCHEMBL19704975 0.82 MGLL (0.35) KMT2AATMMGLL
SCHEMBL5185051 0.81 GRIK1 (0.41) KMT2AATM
SCHEMBL16574558 0.81 GRIK1 (0.41) KMT2AATM
SCHEMBL3912033 0.81 MGLL (0.34) KMT2AATMMGLL
SCHEMBL22198221 0.81 KMT2A (0.36) KMT2AATMMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4341707-A CHEMICAL INTERMEDIATES; PEPTIDE SYNTHESIS Ogura, Haruo (JP) 1982-07-27 US disclosed