SCHEMBL1245548

SCHEMBL1245548

CC(C)CC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
MMP13 P45452 1/20 0.36
KMT2A Q03164 2/20 0.36
ATM Q13315 1/20 0.36
MGLL Q99685 2/20 0.35
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
GLA P06280 1/20 0.33
ALOX15 P16050 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
PIK3CD O00329 1/20 0.32
MIF P14174 1/20 0.32
GAA P10253 1/20 0.32
CA2 P00918 1/20 0.31
ACE P12821 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15643139 0.89 KMT2A (0.36) KMT2AATMMGLLACE
SCHEMBL17929270 0.88 MMP1 (0.32) MMP1MMP2MMP3MMP9MMP13
SCHEMBL17173818 0.88 KMT2A (0.32) MMP1MMP2MMP3MMP9MMP13
SCHEMBL17155176 0.87 MAPK1 (0.35) KMT2AATMMGLLACE
SCHEMBL917156 0.87 GLA (0.34) MMP1MMP2MMP3MMP9MMP13
SCHEMBL5839660 0.86 MGLL (0.33) MMP1MMP2MMP3MMP9MMP13
SCHEMBL11267463 0.85 KMT2A (0.34) KMT2AATMMGLLCA2LMNA
SCHEMBL16310469 0.85 KMT2A (0.37) KMT2AATMMGLLALDH1A1ACE
SCHEMBL19704975 0.85 MGLL (0.35) KMT2AATMMGLLALDH1A1SMN1; SMN2
SCHEMBL22198221 0.84 KMT2A (0.36) KMT2AATMMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11826485-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2023-11-28 US disclosed
US-11795239-B2 Products and methods for monitoring adherence to nucleoside reverse transcriptase inhibitor therapy ORASURE TECHNOLOGIES, INC. (US) 2023-10-24 US disclosed
US-11795239-B2 Products and methods for monitoring adherence to nucleoside reverse transcriptase inhibitor therapy ORASURE TECHNOLOGIES, INC. (US) 2023-10-24 US disclosed
US-11759528-B2 Peg linker and ligand drug conjugate JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2023-09-19 US disclosed
WO-2023161038-A1 SPONGES BASED ON COLLAGEN-LIKE PROTEINS EVONIK OPERATIONS GMBH (DE) 2023-08-31 WO disclosed
WO-2022137156-A1 ARGINASE INHIBITORS AND METHODS OF USE THEREOF Oncoarendi Therapeutics S.A. (PL) 2022-06-30 WO disclosed
US-20220196641-A1 REAGENTS, METHODS, AND SYSTEMS FOR DETECTING THERAPEUTIC AGENTS TO MONITOR ADHERENCE TO NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR METABOLITES ORASURE TECHNOLIGIES, INC. 2022-06-23 US disclosed
US-20220175944-A1 ANTI-CD117 ANTIBODY-DRUG CONJUGATES AND USES THEREOF Magenta Therapeutics, Inc. 2022-06-09 US disclosed
WO-2022118277-A1 CARBONIC ANHYDRASE INHIBITORS SYNTHESIZED ON INTERCONNECTING LINKER CHAINS VILNIUS UNIVERSITY (LT) 2022-06-09 WO disclosed
WO-2021261712-A1 HEMOGLOBIN DERIVATIVE CO-CONJUGATED WITH FATTY ACID-LINKED PEG AND ALKOXY PEG AS A BLOOD SUBSTITUTE SUNBIO, INC. (KR) 2021-12-30 WO disclosed
WO-2004089925-A1 PI-3 KINASE INHIBITOR PRODRUGS SEMAFORE PHARMACEUTICALS, INC. (US) 2004-10-21 WO disclosed
EP-0794788-A4 HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF NEORX CORP (US) 2000-05-24 EP disclosed
EP-0918547-A2 RADIOLABELED ANNEXINS NEORX CORPORATION (US) 1999-06-02 EP disclosed
EP-0799050-A4 RADIOLABELED ANNEXIN-GALACTOSE CLUSTER CONJUGATES NEORX CORP (US) 1998-06-03 EP disclosed
WO-1998004294-A2 RADIOLABELED ANNEXINS NEORX CORPORATION (US) 1998-02-05 WO disclosed
EP-0799050-A1 RADIOLABELED ANNEXIN-GALACTOSE CLUSTER CONJUGATES NEORX CORPORATION (US) 1997-10-08 EP disclosed
EP-0794788-A1 HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF NEORX CORPORATION (US) 1997-09-17 EP disclosed
EP-0759913-A1 AROMATIC AMINE SUBSTITUTED BRIDGED NITROGEN AND SULFUR DONOR ATOM LIGANDS FOR IMAGING NEORX CORPORATION (US) 1997-03-05 EP disclosed
WO-1996017613-A1 HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF NEORX CORPORATION (US) 1996-06-13 WO disclosed
WO-1996017618-A1 RADIOLABELED ANNEXIN-GALACTOSE CLUSTER CONJUGATES NEORX CORPORATION (US) 1996-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795239-B2 Products and methods for monitoring adherence to nucleoside reverse transcriptase inhibitor therapy DNTT, POLRMT, SLC29A1 MMP1 918/4885MMP2 2152/4885MMP3 1595/4885
US-11826485-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices PLOD3, LIG3, PLOD2 MMP1 216/4885MMP2 1229/4885MMP3 2237/4885
US-20220175944-A1 ANTI-CD117 ANTIBODY-DRUG CONJUGATES AND USES THEREOF ITGB7, KIT, CD2 MMP1 4627/4885MMP2 4846/4885MMP3 4308/4885
US-20220196641-A1 REAGENTS, METHODS, AND SYSTEMS FOR DETECTING THERAPEUTIC AGENTS TO MONITOR ADHERENCE TO NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR METABOLITES DNTT, SLC29A1, SAMHD1 MMP1 1653/4885MMP2 3156/4885MMP3 1848/4885
US-11759528-B2 Peg linker and ligand drug conjugate EGFR, MPEG1, ERBB2 MMP1 1978/4885MMP2 1609/4885MMP3 2168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.