Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278570 | 0.84 | HPGD (0.47) | HPGDSMN1; SMN2HTTMAPTNPC1 | |
| SCHEMBL11268727 | 0.82 | SMN1; SMN2 (0.44) | HPGDSMN1; SMN2HTTMAPTNPC1 | |
| SCHEMBL11275087 | 0.82 | HPGD (0.46) | HPGDSMN1; SMN2HTTMAPTNPC1 | |
| SCHEMBL55223 | 0.82 | HPGD (0.46) | HPGDSMN1; SMN2HTTMAPTNPC1 | |
| SCHEMBL11221785 | 0.80 | SMN1; SMN2 (0.46) | HPGDSMN1; SMN2HTTMAPTNPC1 | |
| SCHEMBL11281153 | 0.78 | LMNA (0.51) | HPGDSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL11715776 | 0.72 | HPGD (0.53) | HPGDSMN1; SMN2HTTALOX15MAPT | |
| SCHEMBL11713719 | 0.71 | KMT2A (0.54) | HPGDSMN1; SMN2HTTALOX15MAPT | |
| SCHEMBL2535536 | 0.70 | HPGD (0.96) | HPGDSMN1; SMN2HTTALOX15MAPT | |
| SCHEMBL27723918 | 0.70 | ALDH1A1 (0.82) | HPGDSMN1; SMN2HTTALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343737-A | Process for production of thiolcarbamates and the thiolcarbamates obtained by said process | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1982-08-10 | — | — | US | disclosed |
| US-4298740-A | REACTION OF TERTIARY HALOGEN COMPOUND WITH THIOLCARBAMIC ACID SALT | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |