Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275087 | 0.98 | HPGD (0.46) | SMN1; SMN2GAAHPGDCYP2B6HSD11B1 | |
| SCHEMBL55223 | 0.98 | HPGD (0.46) | SMN1; SMN2GAAHPGDCYP2B6HSD11B1 | |
| SCHEMBL9292283 | 0.86 | SIGMAR1 (0.49) | SMN1; SMN2HPGDALDH1A1HTTUSP2 | |
| SCHEMBL11282002 | 0.84 | ACHE (0.53) | SMN1; SMN2GAAHPGDALDH1A1NPC1 | |
| SCHEMBL11278570 | 0.84 | HPGD (0.47) | SMN1; SMN2GAAHPGDALDH1A1NPC1 | |
| Endothall SCHEMBL4963604 | 0.83 | TFPI2 (0.47) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11276287 | 0.83 | HPGD (0.51) | SMN1; SMN2GAAHPGDALDH1A1MAPK1 | |
| SCHEMBL11268727 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2GAAHPGDHSD11B1ALDH1A1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL15019931 | 0.81 | TSHR (0.43) | SMN1; SMN2GAAHPGDCYP2B6HSD11B1 | |
| SCHEMBL11267680 | 0.80 | HPGD (0.51) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57167903-A | — | — | None | — | — | JP | disclosed |
| JP-S57167903-A | THIOLCARBAMATE HERBICIDAL COMPOSITION | MITSUBISHI PETROCHEM CO LTD | 1982-10-16 | — | — | JP | disclosed |
| US-4343737-A | Process for production of thiolcarbamates and the thiolcarbamates obtained by said process | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1982-08-10 | — | — | US | disclosed |
| US-4298740-A | REACTION OF TERTIARY HALOGEN COMPOUND WITH THIOLCARBAMIC ACID SALT | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |