SCHEMBL11267735

SCHEMBL11267735

OC(Cn1ccnc1)c1ccccc1F

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.55
CYP19A1 P11511 1/20 0.52
HMOX1 P09601 1/20 0.49
AGER Q15109 1/20 0.49
CYP51A1 Q16850 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29669854 0.82 ADRA2C (0.59) ADRA2CCYP19A1HMOX1CYP51A1
SCHEMBL6299467 0.82 ADRA2C (0.59) ADRA2CCYP19A1HMOX1CYP51A1
SCHEMBL6956296 0.82 ADRA2C (0.59) ADRA2CCYP19A1HMOX1CYP51A1
SCHEMBL29669977 0.82 ADRA2C (0.70) ADRA2CCYP19A1HMOX1AGER
SCHEMBL11277181 0.82 ADRA2C (0.70) ADRA2CCYP19A1HMOX1AGER
SCHEMBL27775794 0.81 HMOX2 (0.44) AGER
SCHEMBL9362725 0.81 ADRA2C (0.51) ADRA2CCYP19A1HMOX1AGERCYP51A1
SCHEMBL11250169 0.79 POLB (0.55) ADRA2CCYP19A1HMOX1AGER
SCHEMBL11272488 0.79 ADRA2C (0.52) ADRA2CCYP19A1HMOX1AGERCYP51A1
SCHEMBL9368597 0.79 ADRA2C (0.52) ADRA2CCYP19A1HMOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349556-A Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes BAYER AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed