Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299467 | 1.00 | ADRA2C (0.59) | ADRA2CCYP19A1HMOX1CYP11B1CYP11B2 | |
| SCHEMBL29669854 | 1.00 | ADRA2C (0.59) | ADRA2CCYP19A1HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11635113 | 0.86 | CYP19A1 (0.55) | ADRA2CCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11697349 | 0.85 | CYP19A1 (0.51) | ADRA2CCYP19A1CYP11B1CYP11B2IDO1 | |
| SCHEMBL12781759 | 0.84 | ADRA2C (0.54) | ADRA2CCYP19A1HMOX1CYP11B1CYP11B2 | |
| SCHEMBL6312563 | 0.83 | CYP19A1 (0.45) | ADRA2CCYP19A1CYP11B1CYP11B2IDO1 | |
| SCHEMBL11267735 | 0.82 | ADRA2C (0.55) | ADRA2CCYP19A1HMOX1CYP51A1 | |
| SCHEMBL6299999 | 0.79 | CYP19A1 (0.72) | CYP19A1HMOX1CYP51A1 | |
| SCHEMBL7562437 | 0.79 | CYP19A1 (0.72) | CYP19A1HMOX1CYP51A1 | |
| SCHEMBL29669989 | 0.75 | CYP19A1 (0.62) | ADRA2CCYP19A1HMOX1IDO1CYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969893-A | Acrylamide compound containing azole structure, and preparation method and application thereof | 沈阳药科大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-109320458-B | Diaryl imidazole-containing compound, preparation method and medical application thereof | 中国药科大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-112694472-A | BuChE-IDO1 inhibitor, preparation method and application thereof | 西南大学 | 2021-04-23 | — | — | CN | disclosed |
| EP-1276725-A2 | 5-SUBSTITUTED TETRALONES AS INHIBITORS OF RAS FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001079180-A2 | 5-SUBSTITUTED TETRALONES AS INHIBITORS OF RAS FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 2001-10-25 | — | — | WO | disclosed |