Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300234 | 0.82 | MAPT (0.49) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL29581721 | 0.81 | HSD17B10 (0.53) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL6109697 | 0.81 | HSD17B10 (0.53) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL2608419 | 0.77 | MAPT (0.42) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL11425111 | 0.77 | KMT2A (0.64) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL15423672 | 0.76 | KDM4E (0.41) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL11280556 | 0.74 | GLP1R (0.54) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL5157381 | 0.72 | PIK3CG (0.58) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL30753420 | 0.72 | KDM4E (0.49) | ALDH1A1KDM4EMEN1USP2MAPT | |
| SCHEMBL2368025 | 0.71 | HSD17B10 (0.52) | ALDH1A1KDM4EMEN1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |