SCHEMBL6109697

SCHEMBL6109697

Oc1nc2ccc(Cl)cc2nc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
USP2 O75604 1/20 0.53
KMT2A Q03164 1/20 0.53
PIK3CG P48736 2/20 0.50
PIK3R1 P27986 1/20 0.47
PIK3CA P42336 1/20 0.47
F7 P08709 1/20 0.46
F3 P13726 1/20 0.46
DYRK1A Q13627 1/20 0.46
NR4A2 P43354 1/20 0.42
PIM1 P11309 1/20 0.41
PIM2 Q9P1W9 1/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 1/20 0.41
CDH1 P12830 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581721 1.00 HSD17B10 (0.53) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL11425111 0.86 KMT2A (0.64) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL5157381 0.85 PIK3CG (0.58) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL2368025 0.84 HSD17B10 (0.52) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL11267753 0.81 ALDH1A1 (0.50) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL3994244 0.81 PSMB8 (0.42) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL3696226 0.81 PIM1 (0.56) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL29581162 0.80 TDP1 (0.55) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL404069 0.80 TDP1 (0.55) HSD17B10ALDH1A1MAPTKDM4EMEN1
SCHEMBL15196672 0.80 PIK3CG (0.54) HSD17B10ALDH1A1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454223-B Synthetic method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2022-05-24 CN claimed
CN-111454223-A Synthesis method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2020-07-28 CN claimed
CN-101508051-A Organic solderability preservative pre-dipping agent and organic solderability preservative film forming method YUANBIAO LIN (CN) 2009-08-19 CN claimed
CN-119661530-A Preparation and application of novel anticancer drug TNBG-D compound 重庆医科大学 2025-03-21 CN disclosed
CN-111454223-B Synthetic method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2022-05-24 CN disclosed
CN-111454223-B Synthetic method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2022-05-24 CN disclosed
CN-111454223-B Synthetic method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2022-05-24 CN disclosed
CN-111454223-A Synthesis method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2020-07-28 CN disclosed
CN-111454223-A Synthesis method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2020-07-28 CN disclosed
CN-111454223-A Synthesis method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2020-07-28 CN disclosed
CN-101508051-A Organic solderability preservative pre-dipping agent and organic solderability preservative film forming method YUANBIAO LIN (CN) 2009-08-19 CN disclosed
EP-0339411-A1 Process for the preparation of quinoxalones HOECHST AKTIENGESELLSCHAFT (DE) 1989-11-02 EP disclosed
US-4812458-A 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics A/S FERROSAN (DK) 1989-03-14 US disclosed
EP-0260467-A2 Quinoxaline compounds and their preparation and use NOVO NORDISK A/S (DK) 1988-03-23 EP disclosed
EP-0216299-A1 Quinoxaline derivatives, method for their preparartion and their use to protect cultivated plants against phytotoxical reaction of herbicides BASF Aktiengesellschaft (DE) 1987-04-01 EP disclosed
US-4623725-A [1,2,4]Triazolo[4,3-a]quinoxaline-4-amine derivatives PFIZER INC. (US) 1986-11-18 US disclosed
EP-0107455-B1 TRIAZOLOQUINOXALINES AS ANTIDEPRESSANTS AND ANTIFATIGUE AGENTS PFIZER INC. (US) 1986-07-09 EP disclosed
US-4547501-A Method of using [1,2,4]triazolo[4,3-a]quinoxaline-4-amine derivatives as antidepressant and antifatigue agents PFIZER INC. (US) 1985-10-15 US disclosed
US-4495187-A Method of using [1,2,4]triazolo[4,3-a]quinoxaline-4-amine derivatives as antidepressant and antifatigue agents PFIZER INC. (US) 1985-01-22 US disclosed
EP-0107455-A1 Triazoloquinoxalines as antidepressants and antifatigue agents PFIZER INC. (US) 1984-05-02 EP disclosed