Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157381 | 0.88 | PIK3CG (0.58) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6109697 | 0.84 | HSD17B10 (0.53) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29581721 | 0.84 | HSD17B10 (0.53) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29856205 | 0.81 | NQO2 (0.56) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5157721 | 0.81 | NQO2 (0.56) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL23612607 | 0.79 | NQO2 (0.72) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20475366 | 0.79 | NQO2 (0.72) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL404069 | 0.78 | TDP1 (0.55) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17269519 | 0.78 | PIK3CG (0.54) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29581162 | 0.78 | TDP1 (0.55) | HSD17B10ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | claimed |
| WO-2011117830-A1 | DERIVATIVES OF PHENAZINE USEFUL TO TREAT CANCER | Université de la Méditerranée AIX-Marseille II (FR) | 2011-09-29 | — | — | WO | disclosed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | disclosed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | disclosed |
| EP-2078720-A1 | Novel method for the preparation of derivatives of dihydrotetraazapentacenes, products such as obtained and uses thereof | Université de la Méditerranée - Aix-Marseille II (FR) | 2009-07-15 | — | — | EP | disclosed |
| EP-2078720-A1 | Novel method for the preparation of derivatives of dihydrotetraazapentacenes, products such as obtained and uses thereof | Université de la Méditerranée - Aix-Marseille II (FR) | 2009-07-15 | — | — | EP | disclosed |
| WO-2009083532-A2 | NOVEL METHOD FOR THE PREPARATION OF DERIVATIVES OF DIHYDROTETRAAZAPENTACENES, PRODUCTS SUCH AS OBTAINED, AND USES THEREOF | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083532-A2 | NOVEL METHOD FOR THE PREPARATION OF DERIVATIVES OF DIHYDROTETRAAZAPENTACENES, PRODUCTS SUCH AS OBTAINED, AND USES THEREOF | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2009-07-09 | — | — | WO | disclosed |