Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699148 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10ALOX15CYP1A2 | |
| SCHEMBL2807587 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10ALOX15CYP1A2 | |
| SCHEMBL7492532 | 0.77 | CYP4F2 (0.43) | ALDH1A1HPGDHSD17B10PTPN1CYP4F2 | |
| SCHEMBL7485946 | 0.76 | PTPN1 (0.42) | ALDH1A1HPGDHSD17B10ALOX15PTPN1 | |
| SCHEMBL14739900 | 0.76 | GPR17 (0.62) | ALDH1A1HPGDALOX15PTPN1CYP4F2 | |
| SCHEMBL6383576 | 0.75 | CYP4F2 (0.52) | ALDH1A1HSD17B10PTPN1CYP4F2CYP4A11 | |
| SCHEMBL9357799 | 0.74 | CYP4F2 (0.62) | ALDH1A1PTPN1CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL14740022 | 0.73 | GPR17 (0.61) | ALDH1A1HPGDHSD17B10ALOX15CYP1A2 | |
| SCHEMBL16115828 | 0.73 | CCNC (0.69) | ALDH1A1HPGDHSD17B10ALOX15MAPK1 | |
| SCHEMBL1127003 | 0.73 | GPR17 (0.54) | ALDH1A1HSD17B10CYP1A2CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |