Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126776 | 0.73 | ALDH1A1 (0.53) | KDM4EALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL11172051 | 0.72 | MAPT (0.49) | — | |
| SCHEMBL14739748 | 0.71 | GPR17 (1.00) | GPR17KDM4EALDH1A1FBP1 | |
| SCHEMBL14739170 | 0.70 | GPR17 (1.00) | GPR17KDM4EALDH1A1FBP1 | |
| SCHEMBL2994014 | 0.69 | PTGER4 (0.64) | GPR17FFAR1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL11007304 | 0.68 | PTGER1 (0.54) | GPR17ALDH1A1FFAR1HSD17B10KEAP1 | |
| SCHEMBL8923388 | 0.68 | KDM4E (0.43) | KDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL11162121 | 0.68 | HTT (0.53) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL31212507 | 0.67 | PTGER4 (0.77) | FFAR1KEAP1PTGER1PTGER4PTGER3 | |
| SCHEMBL1261128 | 0.67 | PTGER4 (0.77) | FFAR1KEAP1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |