Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | GRM6 | O15303 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134706 | 0.86 | PRKCZ (0.54) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| SCHEMBL27699148 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDALOX15HTT | |
| SCHEMBL8061323 | 0.80 | HTT (0.54) | ALDH1A1HSD17B10HPGDALOX15HTT | |
| SCHEMBL6503664 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDALOX15HTT | |
| SCHEMBL1126776 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HPGDALOX15HTT | |
| SCHEMBL5730486 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HPGDALOX15HTT | |
| SCHEMBL2576551 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDHTTMAPT | |
| SCHEMBL1126789 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDALOX15HTT | |
| SCHEMBL9805088 | 0.77 | HTT (0.73) | ALDH1A1HSD17B10HPGDALOX15HTT | |
| SCHEMBL2575471 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | disclosed |