SCHEMBL11267799

SCHEMBL11267799

CN(C(=O)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)cc1CCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 1/20 0.42
PTGDR2 Q9Y5Y4 2/20 0.41
TSHR P16473 2/20 0.40
GPR17 Q13304 1/20 0.40
FSCN1 Q16658 1/20 0.40
FFAR1 O14842 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
MAOB P27338 1/20 0.38
LMNA P02545 1/20 0.38
KMO O15229 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MCHR1 Q99705 1/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11260689 0.86 GPBAR1 (0.47) GPBAR1PTGDR2TSHRGPR17FFAR1
SCHEMBL11255784 0.80 GPBAR1 (0.45) GPBAR1FFAR1ALDH1A1
Benzylamine SCHEMBL11271042 0.80 GPBAR1 (0.44) GPBAR1PTGDR2FFAR1SLC6A2SLC6A4
SCHEMBL11267339 0.80 POLB (0.43) GPBAR1PTGDR2TSHRSLC6A4SMN1; SMN2
SCHEMBL11259896 0.80 CDK4 (0.39) PTGDR2TSHRFSCN1FFAR1ALDH1A1
SCHEMBL11260711 0.80 GPBAR1 (0.46) GPBAR1PTGDR2TSHRSLC6A2SLC6A4
SCHEMBL11263458 0.79 GPBAR1 (0.45) GPBAR1PTGDR2TSHRSLC6A2SLC6A4
SCHEMBL11503510 0.78 GPBAR1 (0.44) GPBAR1PTGDR2TSHRGPR17FFAR1
SCHEMBL11264455 0.77 ALDH1A1 (0.42) TSHRFFAR1LMNASMN1; SMN2ALDH1A1
SCHEMBL11269767 0.75 TSHR (0.43) PTGDR2TSHRFFAR1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003532-B1 OMEGA-(2-(N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS, THEIR USE AND PREPARATION, AND MEDICAMENTS CONTAINING THEM Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1982-04-28 EP disclosed
US-4322439-A ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1982-03-30 US disclosed
WO-1979000586-A1 W-(2-N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS,THEIR USE AND PREPARATION,AND MEDICAMENTS CONTAINING THEM BYK GULDEN LOMBERG CHEM FAB (DE) 1979-08-23 WO disclosed
EP-0003532-A1 Omega-(2-(N-lower alkyl-benzamido)-phenyl)-alkanoic acids, their use and preparation, and medicaments containing them Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1979-08-22 EP disclosed