Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265250 | 0.94 | CA12 (0.37) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL11256894 | 0.89 | KMT2A (0.37) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL11253467 | 0.88 | KMT2A (0.39) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11255745 | 0.72 | HTR2C (0.41) | HTR2CRAD52KMT2AMEN1NPC1 | |
| SCHEMBL11255499 | 0.71 | HDAC6 (0.37) | CA1CA2HTR2CRAD52KMT2A | |
| SCHEMBL11256220 | 0.65 | EPHX2 (0.41) | HTR2CRAD52NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4502361 | 0.64 | WNT3A (0.42) | HTR2CRAD52KMT2ANPC1RAB9A | |
| SCHEMBL22832375 | 0.63 | PPARA (0.44) | RAD52KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11265349 | 0.63 | MGLL (0.39) | HTR2CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL11270915 | 0.62 | HTR2C (0.40) | HTR2CRAD52KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |