SCHEMBL11255745 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	HTR2C	P28335	1/20	0.41

▸	RAD52	P43351	1/20	0.41

▸	KMT2A	Q03164	9/20	0.39

▸	MEN1	O00255	6/20	0.39

▸	NPC1	O15118	1/20	0.39

▸	RAB9A	P51151	1/20	0.39

▸	NPSR1	Q6W5P4	1/20	0.39

▸	LMNA	P02545	2/20	0.38

▸	HDAC6	Q9UBN7	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4502145	0.85	HTR2C (0.41)	HTR2CRAD52KMT2AMEN1NPC1
SCHEMBL4501912	0.84	KMT2A (0.43)	HTR2CKMT2AMEN1NPSR1LMNA
SCHEMBL11260856	0.80	HDAC6 (0.43)	HTR2CRAD52KMT2AMEN1NPC1
SCHEMBL11255499	0.78	HDAC6 (0.37)	HTR2CRAD52KMT2AMEN1NPC1
SCHEMBL11265250	0.74	CA12 (0.37)	HTR2CRAD52KMT2AMEN1NPC1
SCHEMBL11256191	0.73	HDAC6 (0.38)	HTR2CRAD52KMT2AMEN1NPC1
SCHEMBL4498347	0.72	WNT3A (0.40)	HTR2CRAD52KMT2AMEN1NPC1
SCHEMBL11256894	0.72	KMT2A (0.37)	HTR2CRAD52KMT2AMEN1NPC1
SCHEMBL4503387	0.72	ALDH1A1 (0.47)	HTR2CRAD52KMT2AMEN1NPC1
SCHEMBL11256677	0.72	HTR2C (0.42)	HTR2CRAD52KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4344946-A	ANTIARTHRITICS, ANTIRHEUMATICS	BOEHRINGER INGELHEIM GMBH (DE)	1982-08-17	—	—	US	disclosed