Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21408329 | 0.76 | KMT2A (0.67) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10965792 | 0.74 | KMT2A (0.44) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11095524 | 0.74 | USP2 (0.49) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11087575 | 0.73 | USP2 (0.41) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11090604 | 0.71 | USP2 (0.39) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11090520 | 0.71 | TSHR (0.47) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17965819 | 0.65 | KMT2A (0.59) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23732222 | 0.65 | KMT2A (0.38) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL69046 | 0.64 | KMT2A (0.69) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8581144 | 0.64 | USP2 (0.44) | USP2KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333878-A | MAKING 1,4-DIALKYLPYRROLE DIESTERS FROM 2-HYDROCARBOXY-1-NITROALKANE AND ENAMINE OF DIALKYL ACETONE DICARBOXYLATE | ETHYL CORPORATION (US) | 1982-06-08 | — | — | US | disclosed |