Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090520 | 0.81 | TSHR (0.47) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL10881348 | 0.80 | ABCB11 (0.41) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL11087575 | 0.80 | USP2 (0.41) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL10923503 | 0.79 | KMT2A (0.46) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL11090604 | 0.78 | USP2 (0.39) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL11085390 | 0.78 | THRB (0.39) | KMT2ATSHRUSP2ALDH1A1NPSR1 | |
| SCHEMBL8608578 | 0.77 | ABCB11 (0.44) | KMT2AMEN1TSHRALDH1A1NPSR1 | |
| SCHEMBL10920481 | 0.76 | TSHR (0.47) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL11268066 | 0.74 | USP2 (0.44) | KMT2ATSHRUSP2ALDH1A1MAPT | |
| SCHEMBL10920459 | 0.69 | KMT2A (0.44) | KMT2AMEN1TSHRUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168658-A1 | Pyrrolecarboxylic acid derivative having analgesic activity, preparation thereof and compositions therefrom | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1986-01-22 | — | — | EP | disclosed |