Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28096355 | 0.98 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| Imidazole Acetic Acid SCHEMBL637983 | 0.77 | — | — | |
| Imidazole Acetic Acid SCHEMBL27340954 | 0.77 | — | — | |
| Imidazole Acetic Acid SCHEMBL9099789 | 0.77 | GABRR1 (0.41) | MAPTKDM4ECYP3A4ALDH1A1CYP1A2 | |
| Imidazole Acetic Acid SCHEMBL2787422 | 0.76 | GABRR1 (0.40) | MAPTKDM4ECYP3A4ALDH1A1CYP1A2 | |
| Imidazole Acetic Acid SCHEMBL28497348 | 0.76 | ALDH1A1 (0.41) | MAPTKDM4ECYP3A4ALDH1A1CYP1A2 | |
| Imidazole Acetic Acid SCHEMBL45374 | 0.76 | ALDH1A1 (0.41) | MAPTKDM4ECYP3A4ALDH1A1CYP1A2 | |
| Imidazole Acetic Acid SCHEMBL27315430 | 0.76 | GABRR1 (0.40) | MAPTKDM4ECYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL5891929 | 0.76 | KCNN4 (0.35) | CYP3A4TDP1ALOX15CES1HIF1A | |
| SCHEMBL4759340 | 0.76 | NPC1 (0.51) | RAB9ANPC1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214600-B1 | CEPHALOSPORIN DERIVATIVES | Otsuka Kagaku Kabushiki Kaisha (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-4906623-A | 3-Imidazolium cephalosporin derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0214600-A2 | Cephalosporin derivatives | Otsuka Kagaku Kabushiki Kaisha (JP) | 1987-03-18 | — | — | EP | disclosed |