Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11295291 | 0.76 | TSHR (0.36) | PTPN1TSHRMEN1KMT2A | |
| SCHEMBL4452264 | 0.74 | TSHR (0.42) | PTPN1TSHRLMNAMEN1KMT2A | |
| SCHEMBL10340794 | 0.73 | HDAC4 (0.31) | ALDH1A1 | |
| SCHEMBL4320538 | 0.73 | ACLY (0.37) | ALDH1A1 | |
| SCHEMBL24360954 | 0.71 | TSHR (0.39) | PTPN1TSHRLMNAMEN1KMT2A | |
| SCHEMBL26101283 | 0.71 | TSHR (0.39) | PTPN1TSHRLMNAMEN1KMT2A | |
| SCHEMBL17378156 | 0.69 | TSHR (0.37) | PTPN1TSHRLMNAMEN1KMT2A | |
| SCHEMBL4455268 | 0.69 | THRB (0.43) | PTPN1TSHRLMNAMEN1KMT2A | |
| SCHEMBL26061856 | 0.69 | TSHR (0.37) | PTPN1TSHRLMNAMEN1KMT2A | |
| SCHEMBL826905 | 0.69 | TSHR (0.46) | PTPN1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357282-A | CONTACTING A FLUORINATED METHYL OR ETHYL EHTER HAVING A METHOXYLATED CARBON ATOM WITH A LEWIS ACID CATALYST ACYLATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-02 | — | — | US | disclosed |