SCHEMBL4320538

SCHEMBL4320538

CCOC(F)(F)C(F)(F)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACLY P53396 2/20 0.37
THRB P10828 1/20 0.36
HDAC4 P56524 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10340794 0.81 HDAC4 (0.31) HDAC4HDAC6ALDH1A1
SCHEMBL16658459 0.79 TSHR (0.32) HDAC4HDAC6ALDH1A1
SCHEMBL7263038 0.79 CES2 (0.39) ALDH1A1
SCHEMBL8769260 0.77 ACLY (0.34) ACLYTHRBALDH1A1
SCHEMBL12762097 0.76 ACLY (0.37) ACLYTHRB
SCHEMBL7262111 0.76 CES2 (0.49)
SCHEMBL9017248 0.75
SCHEMBL16653310 0.73 THRB (0.38) ACLYTHRB
SCHEMBL11268258 0.73 PTPN1 (0.34) ALDH1A1
SCHEMBL11185102 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12319594-B2 Composition and method for capture and degradation of PFAS BATTELLE MEMORIAL INSTITUTE (US) 2025-06-03 US disclosed
US-11891313-B2 Fluidic impedance platform for in-situ detection and quantification of PFAS in groundwater BATTELLE MEMORIAL INSTITUTE (US) 2024-02-06 US disclosed
WO-2023122143-A1 METHODS AND COMPOSITIONS FOR PFAS DEFLUORINATION DETECTION GINKGO BIOWORKS, INC. (US) 2023-06-29 WO disclosed
US-20230089418-A1 COMPOSITION AND METHOD FOR CAPTURE AND DEGRADATION OF PFAS BATTELLE MEMORIAL INSTITUTE (US) 2023-03-23 US disclosed
US-11518689-B2 Composition and method for capture and degradation of PFAS BATTELLE MEMORIAL INSTITUTE (US) 2022-12-06 US disclosed
US-20220252536-A1 FLUIDIC IMPEDANCE PLATFORM FOR IN-SITU DETECTION AND QUANTIFICATION OF PFAS IN GROUNDWATER BATTELLE MEMORIAL INSTITUTE (US) 2022-08-11 US disclosed
US-20210318613-A9 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2021-10-14 US disclosed
US-20200393761-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2020-12-17 US disclosed
EP-2094633-B1 HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE 3M INNOVATIVE PROPERTIES CO (US) 2017-08-02 EP disclosed
US-8193397-B2 Comprising terminal (perfluoroalkyl) groups and intervening oxytetrafluoroethylidene moiety bonded through its central carbon atom to an alkoxy- or fluoroalkoxy-substituted fluoromethylene moiety, each of said terminal having at least one catenated heteroatom; ozone depletion potential, global warming 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-06-05 US disclosed
EP-2094633-A1 HYDROFLUOROETH R COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE 3M Innovative Properties Company (US) 2009-09-02 EP disclosed
WO-2008070606-A1 HYDROFLUOROETHΞR COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-06-12 WO disclosed
US-20080139683-A1 HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE 3M INNOVATIVE PROPERTIES COMPANY 2008-06-12 US disclosed
EP-1253133-B1 Process of preparing halogenated esters 3M INNOVATIVE PROPERTIES CO (US) 2004-10-06 EP disclosed
US-6703520-B2 REACTING AN ESTER WITH HALOGENATED UNSATURATED COMPOUND 3M INNOVATIVE PROPERTIES COMPANY 2004-03-09 US disclosed
US-20020177729-A1 Process of preparing halogenated esters 3M INNOVATIVE PROPERTIES COMPANY 2002-11-28 US disclosed
WO-2002085837-A1 PROCESS OF PREPARING HALOGENATED ESTERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-10-31 WO disclosed
EP-1253133-A1 Process of preparing halogenated esters 3M Innovative Properties Company (US) 2002-10-30 EP disclosed
US-5206422-A Process for preparation of fluorinated carbonyl compounds THE DOW CHEMICAL COMPANY (US) 1993-04-27 US disclosed
US-4357282-A CONTACTING A FLUORINATED METHYL OR ETHYL EHTER HAVING A METHOXYLATED CARBON ATOM WITH A LEWIS ACID CATALYST ACYLATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139683-A1 HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE OGFOD1, AQP3, FOS ACLY 4386/4885THRB 909/4885HDAC4 3666/4885
US-20020177729-A1 Process of preparing halogenated esters ELOVL3, ELOVL1, EBP ACLY 3686/4885THRB 1989/4885HDAC4 1245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.