Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10331892 | 0.97 | — | — | |
| SCHEMBL11334655 | 0.78 | MAPT (0.32) | ALDH1A1LMNA | |
| SCHEMBL6562046 | 0.73 | TDP1 (0.37) | — | |
| SCHEMBL27772136 | 0.73 | — | — | |
| SCHEMBL862169 | 0.73 | — | — | |
| SCHEMBL8196368 | 0.72 | — | — | |
| SCHEMBL10817076 | 0.72 | — | — | |
| SCHEMBL1820735 | 0.70 | — | — | |
| SCHEMBL8344802 | 0.70 | ALDH1A1 (0.33) | ALDH1A1HSD17B10LMNAHPGDALOX15 | |
| SCHEMBL5214706 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353913-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| US-4287199-A | USEFUL AS ANTHELMINITICS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-01 | — | — | US | disclosed |
| EP-0009174-A1 | Novel (5-(3,4-dihydroisoquinolin-1-yl)-1H-benzimidazol-2-yl)-carbamic acid alkylesters, processes for the production thereof, medicaments based on said compounds and process for the production of anthelmintic agents | BAYER AG (DE) | 1980-04-02 | — | — | EP | disclosed |