Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268394 | 1.00 | CRBN (0.47) | CRBNDDB1NPC1RAB9AALOX15 | |
| SCHEMBL9266208 | 0.72 | CRBN (0.41) | CRBNDDB1PKM | |
| SCHEMBL23119506 | 0.70 | CRBN (0.50) | CRBNDDB1ALDH1A1LMNAPKM | |
| SCHEMBL21439798 | 0.70 | ALOX15 (0.67) | NPC1RAB9AALOX15ALDH1A1LMNA | |
| SCHEMBL21439799 | 0.70 | ALOX15 (0.67) | NPC1RAB9AALOX15ALDH1A1LMNA | |
| SCHEMBL7056284 | 0.69 | CRBN (0.45) | CRBNDDB1ALDH1A1LMNAPKM | |
| SCHEMBL9661028 | 0.67 | ALOX15 (0.54) | NPC1RAB9AALOX15ALDH1A1LMNA | |
| SCHEMBL10410969 | 0.67 | ALOX15 (0.54) | NPC1RAB9AALOX15ALDH1A1LMNA | |
| SCHEMBL28252568 | 0.66 | CRBN (0.45) | CRBNDDB1ALDH1A1LMNAPKM | |
| SCHEMBL11713868 | 0.66 | CRBN (0.50) | CRBNDDB1ALDH1A1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348518-A | Cephalosporins | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |
| US-4091211-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-23 | — | — | US | disclosed |