Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661028 | 1.00 | ALOX15 (0.54) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL27498504 | 0.71 | ALOX15 (0.43) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL10410397 | 0.68 | MEN1 (0.54) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL10429290 | 0.68 | NPC1 (0.44) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL9661945 | 0.68 | NPC1 (0.44) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL9661641 | 0.68 | MEN1 (0.54) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL11268402 | 0.67 | CRBN (0.47) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL11268394 | 0.67 | CRBN (0.47) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL16773839 | 0.67 | MAPT (0.61) | ALOX15MAPTGAARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10429295 | 0.64 | MEN1 (0.46) | ALOX15MAPTGAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956470-A | BACTERICIDES, FUNGICIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4908363-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | disclosed |
| US-4814332-A | PARASITICIDES | HOFFMAN-LA ROCHE INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0253084-A2 | 1,3-Disubstituted imidazolium salts | F. HOFFMANN-LA ROCHE AG (CH) | 1988-01-20 | — | — | EP | disclosed |