Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21439798 | 1.00 | ALOX15 (0.67) | ALOX15NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8011202 | 0.83 | SMN1; SMN2 (0.52) | ALOX15NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL11268394 | 0.70 | CRBN (0.47) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11268402 | 0.70 | CRBN (0.47) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2494935 | 0.65 | LMNA (0.79) | NPC1RAB9AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL2494933 | 0.65 | LMNA (0.79) | NPC1RAB9AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3518937 | 0.65 | HTT (0.62) | RAB9AALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL31499008 | 0.65 | ALDH1A1 (0.73) | ALOX15NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL28280836 | 0.64 | MEN1 (0.59) | ALOX15NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL10410969 | 0.63 | ALOX15 (0.54) | ALOX15NPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021066149-A1 | PHARMACEUTICAL COMPOSITION AND KIT CHARACTERIZED BY CONTAINING NOVEL PENAM DERIVATIVE OR SALT THEREOF AND ONE OR MORE COMPOUNDS SELECTED FROM Β-LACTAMASE INHIBITOR COMPOUND, ANTIBACTERIAL COMPOUND AND SALTS OF THESE | 富士フイルム株式会社 | 2021-04-08 | — | — | WO | disclosed |
| WO-2019194306-A1 | NOVEL PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | 富士フイルム株式会社 | 2019-10-10 | — | — | WO | disclosed |