Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | CASP1 | P29466 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269247 | 0.85 | KDM4E (0.49) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL11265870 | 0.84 | KDM4E (0.48) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL11280553 | 0.82 | KDM4E (0.46) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL11270980 | 0.80 | AGTR1 (0.45) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL28665936 | 0.79 | KDM4E (0.64) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL22421592 | 0.78 | POLR1A (0.56) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| Doqualast SCHEMBL124450 | 0.77 | KDM4E (0.63) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL21798938 | 0.76 | KDM4E (0.69) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL11617862 | 0.75 | ALPG (0.43) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL2217810 | 0.72 | KDM4E (0.62) | ALDH1A1HPGDGAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |