Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLR1A | O95602 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268488 | 0.84 | ALDH1A1 (0.62) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL11269247 | 0.81 | KDM4E (0.49) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL11280553 | 0.79 | KDM4E (0.46) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL11270980 | 0.77 | AGTR1 (0.45) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| Doqualast SCHEMBL124450 | 0.74 | KDM4E (0.63) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL11617862 | 0.72 | ALPG (0.43) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL11275156 | 0.72 | ALPG (0.60) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL21798938 | 0.71 | KDM4E (0.69) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL21798961 | 0.69 | KDM4E (0.71) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL21798922 | 0.68 | KDM4E (0.69) | KDM4ECASP1CASP7HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |