Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | C5 | P01031 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106284 | 0.85 | PTGS2 (0.50) | PTGS2MEN1MAPTKMT2AABCC4 | |
| SCHEMBL31324164 | 0.83 | MEN1 (0.69) | PTGS2MEN1MAPTKMT2AABCC4 | |
| Methane SCHEMBL506242 | 0.82 | MEN1 (0.67) | PTGS2MEN1MAPTKMT2AABCC4 | |
| SCHEMBL31324193 | 0.77 | MEN1 (0.73) | PTGS2MEN1MAPTKMT2AABCC4 | |
| Carprofen SCHEMBL516074 | 0.77 | PTGS2 (0.80) | PTGS2MEN1MAPTKMT2AABCC4 | |
| SCHEMBL8161592 | 0.77 | PTGS2 (0.48) | PTGS2MEN1MAPTKMT2AABCC4 | |
| SCHEMBL8004981 | 0.76 | KIF11 (0.65) | PTGS2MEN1MAPTKMT2AABCC4 | |
| SCHEMBL31324154 | 0.76 | PTGS2 (0.51) | PTGS2MEN1MAPTKMT2AABCC4 | |
| SCHEMBL11018311 | 0.76 | PTGS2 (0.51) | PTGS2MEN1MAPTKMT2AABCC4 | |
| Carprofen SCHEMBL3910 | 0.75 | PTGS2 (1.00) | PTGS2MEN1MAPTKMT2AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008446-B1 | PROCESS FOR THE PREPARATION OF CARBAZOLES AND NOVEL CARBAZOLE DERIVATIVES UTILIZED THEREIN | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-09-22 | — | — | EP | claimed |